The endohedral metallofullerenol Gd@C82(OH)22 has been identified as a possible antineoplastic agent that can inhibit both the growth and metastasis of cancer cells.Despite these potentially important effects, our understanding of the interactions between Gd@C82(OH)22 and biomacromolecules remains incomplete.Here, we study the interaction between G
Background Clinical benefit from programmed cell death 1 receptor (PD-1) inhibitors HAWTHORN FLOWERS AND LEAVES relies on reinvigoration of endogenous antitumor immunity.Nonetheless, robust immunological markers, based on circulating immune cell subsets associated with therapeutic efficacy are yet to be validated.Methods We isolated peripheral bloo
Background: Rehabilitation is vital for optimizing recovery following neurological injuries.However, much of what is done for the paediatric population relies heavily on the adult literature or is based on expert opinion.No previous attempt has been made to collate high-quality evidence pertaining to the subacute period.Objectives: To summarize and
Objectives (1) Develop a programme theory of why, for whom and in what contexts integrated palliative care (PC) and heart failure (HF) services work/do not work; (2) use the programme theory to co-produce with stakeholders, intervention strategies to inform best practice and future research.Methods A systematic review of all published articles and